CBD is fast becoming a big industry, especially in some Asian countries. And the biggest concerns that consumers and experts come across are CBD drug interactions, i.e., the fear of not knowing whether CBD is safe to take with other medications. This is indeed a serious issue for experts’ considerations. It requires deep thought and inquiry, considering the ambiguity of what is really in some prescribed medications and how they work with the body. Research shows that CBD is generally safe and has few minor side effects. However, there is one big challenge, i.e., whether CBD can interact with some medications. The concern has to do with how the body metabolizes certain substances.
Before trying CBD, it is therefore essential to discuss with your doctor about all of the vitamins, supplements, and prescription and over-the-counter medications you are taking. Below is a set of facts about why having a conversation with your doctor matters.
1. There is no doubt that CBD can deliver various health benefits and is safe to take with many medications. Still, CBD can create problematic interactions with certain drugs. For instance, labels on a variety of prescription drugs will advise you to avoid grapefruit when taking CBD medication because it can significantly affect how the body metabolizes the drug. When you take a medication or other substance, your body has to metabolize it or break it down. It has been discovered that drug metabolism happens throughout the body, such as in the gut. But the liver does a big part of the job. Science has it that a family of enzymes called cytochrome P450 does the vital work of converting drugs or swallowed substances so they can easily be eliminated from the body. But some medications or substances affect CYP450, either by slowing or speeding up drug metabolism. That change in metabolism rate can alter how your body processes the medications or supplements you take. This is what is known as a drug interaction. It is suggested that under the careful supervision of your doctor, you might still be able to safely use CBD with medications, even those with grapefruit warning.
2. In another dimension, the reverse can happen. Scientific studies reveal that some medications inhibit, slow down, and alter the effectiveness of CYP3A4. If CBD is taken while on these medications, your body cannot work to process it as effectively as required. This is what we consider to be CBD interactions with other drugs or food supplements in the human body. The danger here is that one may have more than required CBD contents in one’s body at one time than intended, even if you have stuck to your regular dose. An increased level of medication in your system could exaggerate its effects, including unwanted or harmful side effects of CBD drugs.
3. Also noted through science is that some substances also speed up the work of the CYP450 enzyme family. If your body is metabolizing a medication too fast because another substance is inducing the enzymes, you may not have enough medication in your system to treat a health issue. This is another angle of viewing the scientific discovery of the CBD oil interactions with medications.
4. It is imperative always to consult your doctor if you would like to try CBD, especially if you have a health condition that requires you to take medications. Do not stop taking your prescription medications to try CBD, unless you have the go-ahead from your doctor. Even if you take one of the medications for which abstinence from grapes juice is disallowed, your doctor might formulate a plan that works for you through close monitoring of medication levels in your system. That way, you can use both your prescription and CBD as a therapy. This is a plan that your doctor is capable of managing for you.
5. It must be known that findings are not always conclusive on the CBD oil interactions with medications, as further research is still needed. CBD can have adverse interactions with a drug depending on the type, quality, and purity of CBD being administered. It is therefore highly advised that a doctor or a certified health professional is consulted before taking Cannabidiol (CBD).
6. It is also noted that by slowing down how the body metabolizes these drugs, CBD preserves the medications’ durability and prolongs its presence in the body. This is an indication that CBD can increase and prolong the effects of drugs. However, this increases the risk of bleeding. The usage of both (CBD and Medication) simultaneously should be closely monitored by a medical professional.
7. When CDB oil interacts with neurotransmitter receptors in the central nervous system, cannabinoids like CBD and THC can induce sedative effects on the user. The sedative effects of THC are associated with drowsiness and lethargy. CBD induces sedative effects that are calming and wake-inducing. When combined, CBD oil with sedatives produces an additive effect, meaning they can increase the impact of the medication. While CBD and sedatives’ interaction does not seem to have a directly negative impact on the user, CBD’s potential impact on sedatives is not fully known.
8. The interactions of CBD oil with Anti-Seizure Medication and Chemotherapy Drugs could be adverse. CBD is widely known to be an effective treatment for epileptic seizures. However, research has revealed that without medical supervision, it can present problems under certain circumstances with anti-seizure medication. As for chemotherapy drugs, they are most often formulated to understand that the drug will undergo metabolism at a specific rate before entering the body. When CBD is introduced to the drug plan, the metabolism process is hampered or inhibited, resulting in higher concentrations of the drug to enter the bloodstream than intended.