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We have a diverse workforce that strives to provide the best services to our clients

JOHN SNOW
JOHN SNOWAnethesiologist
TONY STARK
TONY STARKCardiologist
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ANNA SMITHNurse

HEALTH UPDATES

Epidiolex for Epilepsy

CBDWhat is Epidiolex?
Epidiolex is a pharmaceutical drug derived directly from Marijuana. Cannabidiol (CBD), as it is medically known, is an oral solution made from highly-purified Cannabis. The component responsible is part of the two main compounds that build the marijuana plant. The other part is Tetrahydrocannabinol (THC) and is responsible for psychoactive effects on users. There is an insignificant amount of THC in Epidiolex hence no need to worry about getting high from its use.

GW is the pharmaceutical company responsible for creation of CBD, as the answer to epilepsy medication. The British firm is focused on the discovery, development and sale of novel therapeutics from Bioscience.

The approval of Edpidiolex by huge bodies such as American Food and Drug Administration (FDA) has created a surge in demand for the drug globally. This was the historic milestone that changed the world’s view of marijuana and it uses in modern medicine. CBD is under scrutiny by the European Medicine Agency (EMA) before recommendation as safe medication for seizures in children. GW pharmaceuticals submitted a marketing authorization application (MAA) to the EMA and expects recommendation early in 2019. After numerous clinical trials, this medication was proven consistently helpful in treatment of specifically pediatric populations.

The director of pediatric epilepsy programs at Massachusetts General Hospital is one of the first doctors to recommend the drug for families frustrated by the difficult-to-treat forms of epilepsy. The drug is useful in treatment of seizures. Specifically, it is effective on seizures related to Lennox-Gastaut (LGS) and Dravet syndrome of patients older than 2 years of age. These are the most severe and stubborn forms of childhood-onset seizures. They have proved so challenging that not many of families struggling with this problem ever achieve ultimate control. Treatment-resistant epilepsies are stubborn and there are many patients desperate to try out anything that trends as medication for seizures.

Marijuana ediblesThe Creation of Epidolex
The cbd clinical development program included three random trials as well as an open-label extension study. It was found to consistently reducing the frequency of seizures among children diagnosed with LGS and Dravet Syndrome. Rescheduling is necessary before supply of the drug to the public. There is a 90-day period from its current first schedule before availing the medication to patients. It joins other brands such as AEDs.

 

 

 

The cbd development program for rare and severe conditions brings hope to patients and their families. It has the potential of not only reducing the frequency of seizures but also eliminating the condition. The drug will be supplied in the United States by Greenwich Biosciences, which is the American subsidiary of GW Pharmaceuticals. GW Pharmaceuticals development program represents the reliable clinical evaluation of Cannabinoid medication for patients.

Side Effects
For the subjects that participated in the tests, the most common reactions associated with the medication included decreased appetite and somnolence, rash, malaise, transaminase elevations, and fatigue. Other adverse reactions include diarrhea, asthenia, insomnia, and sleep disorders.

Epidiolex use is also associated with liver problems. You therefore, need to consult with your doctor before proceeding with its use. There are cases where treatment needs to be halted because of the danger it poses to your healthcare. Symptoms of reactions include yellowing of skin and whitening of the patient’s eyes. Some people may also experience itching but there is mostly darkening of the urine among many patients.

Mild side effects include; discomfort, and stomach area. When on other medications such as Clobazam, a patient may have intense reaction in sleepiness. Alcohol also produces the same effects and should be avoided. Refrain from driving, operating heavy machinery and other involving activities that may endanger you and other people if Epidiolex affects you.

Marijuana ediblesSome people may experience suicidal tendencies but this is rare and occurs in very few people. It is only recorded in 1 out of every 500 users. This effect is like most other traditional antiepileptic drugs before it. If you have any of the symptoms, it is advisable to seek the attention of your healthcare provider. To the subjects who experienced suicidal tendencies, most reported thoughts of dying, attempting to commit suicide, worsening depression, increase in anxiety, agitation, restlessness, panic attacks, and irritability. Other symptoms include; bursts of anger and violence, excessive aggressiveness, acting dangerously, insomnia, and mood changes.

Watch out for early symptoms of suicidal thoughts and actions to keep your patient safe from harm. Record any behavioral changes that are sudden. Pay close attention to mood changes, and reactions from relating with the engagement. Follow up with visits to the healthcare provider to be a step ahead of serious side effects.

You should not halt Epidolex oral intake without the advice from your healthcare provider. Avoid making decisions based on your feelings. Making uninformed decisions may cause more harm than good. For example, sudden changes in cbd treatment such as immediately stopping the medication may result in uneven occurrence of seizures. This is called Status epilepticus.

Conclusion
The American Foods and Drugs Association’s decision to approve use of cbd medication for epilepsy in children has raised concerns as well as huge debates. Its retraction from Marijuana is the cause for debate, mostly based on morality. Most people are suspicious overt the inclusion of THC compound and its safety to young patients. Desperate families with children diagnosed with LGS and Dravet Syndrome have embraced the idea because they are ready to try any recommendable medication. GW Pharmaceuticals has proven its authenticity and positive impact on the condition and revealed the side effects too.

 

The Novus CBD Health Plan

CBD OilNovus MedPlan is a widely known supplemental health plan that focuses on patient treatment costs so that a budget-friendly solution can be recommended to the consumers. This program is launched by Frank Labrozzi, Novus CEO and Chairman; in a recent interview he said that CBD products are not just useful for patients around; rather at the same time, it is useful for the cultivators and dispensaries as well.

The Novus CBD health plan works to meet a variety of needs of the patients. Including naturopathic, vision related, dental, and diabetic health care. The best thing to know about this platform is that they offer budget-friendly purchase options for the treatment of most of the medical health problems.

Novus is currently working to provide direct benefits to the consumers for the products that are listed on the online portal of MedPlan. Novus is currently applying health plan discounts on various products, but the most important factor to consider at this point is that transaction usually occurs between the company and the patient directly at the time when they make a purchase. In order to sell the products at a set discount, the partnering companies are integrated in advance. Note that, in order to combat the losses that companies may face after providing huge discounts to the customers, Novus offers potential advertising and marketing services online.

The partnering companies have member access on Novus platform, and they are able to maintain an instant web presence on the online shop maintained by Novus. At present, Novus is also making efforts to add some manufacturers, cultivators, and dispensaries to the vertically integrated platform to serve customer needs with ease.

Stats reveal that Novus follows typical state-level regulations to advertise their partners online. The members count in the Novus teams these days have increased up to 15000 whereas the marketing cost goes as high as up to 1.3 million.

CBD OilNovus started its operation in the year 2015, and at present, they are strictly working only on the state level; however, the brand plans to grow overseas with federal legalization of marijuana and CBD products. You might be aware of the fact that the medical marijuana system in Canada is federally regulated. However, as regulations in the United States rely on state0-based rules and insurance plans; Novus is waiting for approval in all states so that all risk and non-risk plans can be sold with ease.

Currently, the full plan for patients on a monthly basis is $24.95 with copays, long-term contracts, and deductibles. The applications usually get fast approval on Novus MedPlan network. In general, if a patient needs to spend $150 per month for buying cannabis medications; Novus plan can help him to save almost $1000 per year. With the advancements in technologies, Novus plans have become fully automated. Patients simply need to visit the company website and fill the application form online. The applications are processed shortly, and they can make purchases from network members at a great discount. Indeed, Novus Rx discounts offer the best way to save on CBD purchase online.

How to bring Your Medication with You

CBD capsule The bustles and hustle of daily lives can make us forget most of our body needs and therapy; exercise, resting, taking medications. Most of the time, we start our dosing and never complete it, and this can cost us full recoveries from the illness not to mention exposing our immune system. Most medications like CBD supplements, are taken at intervals either to relax the body or as a relief to ailment and illnesses. Also, while taking medications in public places or while ‘on the move’ we want to be discreet so as not to attract suspicious glances from onlookers.

Medications and legislation in the country
The use of CBD in the U.S has been legalized in the country by the Farm Act of 2018; which makes the purchase, sale, and possession of CBD legal in most states of the country.

How to move about with your medications
Solutions to skipping medications and drugs like CBD due to forgetfulness can be to

  • Use calendar and notifications alerts
  • Tying your medication doses with daily activities
  • Get help from family members and friends

https://www.youtube.com/watch?v=c8To81VFggA

Keeping an up to date list of your medications
The best solution is to carry them in small compatible and portable pouches or containers. Examples of such containers could be Pillboxes, compartment jewelry, etc.

Pillboxes
These boxes are fashionably designed so that they can house your pills and CBD capsules discreetly and conveniently.

poison ringThe water bottle/pillbox combo
More like a 2-in-1 combination of both a pill compartment and a space to keep water that fits into your pocket. With this type of pillbox, you won’t have to swallow your CBD capsules dryly.

Macaron pill container
Shaped perfectly round like large-sized candy, you would be careful not to eat them. They can contain a fair amount of pills/capsules and can be easily slipped into your pockets. You reveal the hidden pills by uncoupling the identical set.

Travel-friendly pill organizer
These are larger and are used for when they are different pills, which means they are more suited to long-distance travel. Their cases also contain different colors that can help you arrange your pills.

  • The squeeze-open pouch
  • Lacquer pill cases (handcrafted)

CBD capsules
Capsules are pills that have the CBD oils and compounds in them, including other vitamins and terpenes. They are also very portable, easy to store, and do not cause any allergies or reactions. This makes the use of CBD capsules more viable options for moving about with your CBD. It is more convenient and discreet when compared to other intake methods.

CBD capsulePoison rings
These are compartment jewelry with bezels/compartments to store small objects like poison, little mementos, and drugs. They are so-called poison rings because, in earlier times, it was used to store a bit of arsenic or other poison powders to attack enemies. Now, poison rings are used primarily as a fashion trend or style. The compartments are usually large enough, but deftly hidden to onlookers. With poison rings, you can slip the ring as part of your dressing, while carefully placing your CBD capsules inside the compartments. Examples of the poison rings that can be used for your capsules are the

  • Victorian scroll poison ring
  • The metal clay Guru
  • Strong-box ring
  • Open-box ring
  • The mystic chamber silver ring.

Conclusions
There are different methods of methods that are used to ‘hide’ your CBD. Choosing the best method is a personal decision, and should fit with your style.

Is it Safe to Take CBD with Other Medications?

can cbd oil interact with medicationsCBD is the new “miracle drug.” People use it for everything from anxiety to pain relief to epilepsy treatment. The list of benefits is a long one, and it is growing all the time as researchers continue to study CBD use. As more and more people continue to use it for treatment, many are starting to ask, “Can CBD oil interact with medications?” People often choose to use CBD because they want a more natural option that does not produce as many negative side effects as their medications. CBD alone is generally considered safe, and there are only minor side effects, such as drowsiness. However, it can still be risky to take along with other medications, and CBD interactions can potentially be dangerous. Experts like to remind people that all drugs, even herbal drugs, interact with each other.

All medications have to be metabolized in the body, most often in the gut or liver. One particular enzyme family is called the cytochrome P450. These enzymes are responsible for metabolizing more than half of all prescription medications. This enzyme family converts all foreign substances, enabling them to leave the body. CBD is also metabolized by the cytochrome P450, meaning it can inhibit these enzymes and negatively interact with any medication that is metabolized by this enzyme family. CBD competes with these medications and either slows or speeds up their metabolism. This change affects how the body processes these medications. In some cases, CBD can cause high levels of medications to stay in the body longer than they are supposed to, which can cause an increase in side effects or even an overdose.

In other cases, the CBD can cause the medications to be less effective by speeding up the metabolization process. If a medication is metabolized too quickly, it may not stay in your system long enough to do its job. Regardless of whether CBD slows down or speeds up the process, the dosage would need to be adjusted correctly to stop this from happening.

There are many types of medications known to be affected by CBD use, such as steroids, antidepressants, heart medications, and antibiotics. CBD can increase medications that cause blood-thinning, such as ibuprofen. Since CBD causes the metabolism to slow down, these medications stay in the body longer than they should, prolonging their effects. CBD can sometimes cause drowsiness in users, so it should also never be taken with sedatives as it will only increase the sedative effects. Although studies have shown that CBD can be an effective epilepsy treatment, and has been developed into a prescription medication, using CBD while taking any other epilepsy medication can have negative effects. Instead of providing better treatment, as was once hoped, this combination can actually cause more aggressive seizures. A similar reaction can occur when taking medication for chemotherapy. Even though CBD alone can be beneficial for cancer patients, using it while taking chemotherapy drugs can result in a high concentration of the medication entering the bloodstream. In both cases, negative effects could be reduced by decreasing the medication dosage, but most doctors would suggest not combining these medications with CBD at all.

cbd interactionsSince researchers are still studying to figure out all the medications CBD interacts with, a simple Google search will not always suffice. Experts agree that if you are not sure if CBD will interact with your medication, you can look for a grapefruit warning on the label. Over eighty-five medications are currently known to interact with grapefruit and even other citrus juices, such as orange juice. These medications can become less effective if the user eats grapefruit or drinks grapefruit juice. Like CBD, grapefruits contain chemicals that affect the cytochrome P450 enzyme family.

Consuming grapefruit while taking these medications leads to high concentrations of the medication in the bloodstream. It can also result in negative side effects or overdose, just like CBD. The general rule of thumb is that if a medication has a grapefruit warning, you should not take CBD with it either. It is believed that CBD interactions could be worse for elderly people. The work of their livers and kidneys slows down as people get older, meaning medications are eliminated from the body at a slower rate. Many elderly people use more than one medication, so the risk of interaction is even greater. These interactions could result in dizziness and a higher risk of falling, which puts them in more danger than younger people.

Researchers are working hard to learn all they can about CBD interactions. So far, most of the tests have been done have been on animals, so it is hard to say how this research will differ in humans. There are also some studies that contradict each other, only adding to the confusion of this research. Some studies show that smaller doses of CBD can interact with medications less, while other studies have not shown significant changes when the dosage was decreased. So, can CBD oil interact with medications? Yes, but it is important to talk to your doctor before using CBD, especially while taking other medications.

cbd interactionsIt is important for your doctor to know about anything else you are taking, including over-the-counter medications and vitamins. Your doctor may be able to help you come up with a plan that allows you to use your medications and CBD together in a safe manner while monitoring any possible side effects. They can help determine a safe dosage of each and a schedule to follow to maximize the benefits of both. Although some doctors will not recommend the use of CBD in any case, many recognize the potential benefits and they are hopeful that it can offer relief to their patients. In some cases, they may recommend a form of CBD that is not ingested, like topical products, because they do not enter the bloodstream like oils, vapors, or edibles.

CBD Drug Interactions

can cbd oil interact with medicationsCBD is fast becoming a big industry, especially in some Asian countries. And the biggest concerns that consumers and experts come across are CBD drug interactions, i.e., the fear of not knowing whether CBD is safe to take with other medications. This is indeed a serious issue for experts’ considerations. It requires deep thought and inquiry, considering the ambiguity of what is really in some prescribed medications and how they work with the body. Research shows that CBD is generally safe and has few minor side effects. However, there is one big challenge, i.e., whether CBD can interact with some medications. The concern has to do with how the body metabolizes certain substances.

Before trying CBD, it is therefore essential to discuss with your doctor about all of the vitamins, supplements, and prescription and over-the-counter medications you are taking. Below is a set of facts about why having a conversation with your doctor matters.

1. There is no doubt that CBD can deliver various health benefits and is safe to take with many medications. Still, CBD can create problematic interactions with certain drugs. For instance, labels on a variety of prescription drugs will advise you to avoid grapefruit when taking CBD medication because it can significantly affect how the body metabolizes the drug. When you take a medication or other substance, your body has to metabolize it or break it down. It has been discovered that drug metabolism happens throughout the body, such as in the gut. But the liver does a big part of the job. Science has it that a family of enzymes called cytochrome P450 does the vital work of converting drugs or swallowed substances so they can easily be eliminated from the body. But some medications or substances affect CYP450, either by slowing or speeding up drug metabolism. That change in metabolism rate can alter how your body processes the medications or supplements you take. This is what is known as a drug interaction. It is suggested that under the careful supervision of your doctor, you might still be able to safely use CBD with medications, even those with grapefruit warning.

2. In another dimension, the reverse can happen. Scientific studies reveal that some medications inhibit, slow down, and alter the effectiveness of CYP3A4. If CBD is taken while on these medications, your body cannot work to process it as effectively as required. This is what we consider to be CBD interactions with other drugs or food supplements in the human body. The danger here is that one may have more than required CBD contents in one’s body at one time than intended, even if you have stuck to your regular dose. An increased level of medication in your system could exaggerate its effects, including unwanted or harmful side effects of CBD drugs.

can cbd oil interact with medications

3. Also noted through science is that some substances also speed up the work of the CYP450 enzyme family. If your body is metabolizing a medication too fast because another substance is inducing the enzymes, you may not have enough medication in your system to treat a health issue. This is another angle of viewing the scientific discovery of the CBD oil interactions with medications.

 

4. It is imperative always to consult your doctor if you would like to try CBD, especially if you have a health condition that requires you to take medications. Do not stop taking your prescription medications to try CBD, unless you have the go-ahead from your doctor. Even if you take one of the medications for which abstinence from grapes juice is disallowed, your doctor might formulate a plan that works for you through close monitoring of medication levels in your system. That way, you can use both your prescription and CBD as a therapy. This is a plan that your doctor is capable of managing for you.

5. It must be known that findings are not always conclusive on the CBD oil interactions with medications, as further research is still needed. CBD can have adverse interactions with a drug depending on the type, quality, and purity of CBD being administered. It is therefore highly advised that a doctor or a certified health professional is consulted before taking Cannabidiol (CBD).

cbd interactions6. It is also noted that by slowing down how the body metabolizes these drugs, CBD preserves the medications’ durability and prolongs its presence in the body. This is an indication that CBD can increase and prolong the effects of drugs. However, this increases the risk of bleeding. The usage of both (CBD and Medication) simultaneously should be closely monitored by a medical professional.

7. When CDB oil interacts with neurotransmitter receptors in the central nervous system, cannabinoids like CBD and THC can induce sedative effects on the user. The sedative effects of THC are associated with drowsiness and lethargy. CBD induces sedative effects that are calming and wake-inducing. When combined, CBD oil with sedatives produces an additive effect, meaning they can increase the impact of the medication. While CBD and sedatives’ interaction does not seem to have a directly negative impact on the user, CBD’s potential impact on sedatives is not fully known.

8. The interactions of CBD oil with Anti-Seizure Medication and Chemotherapy Drugs could be adverse. CBD is widely known to be an effective treatment for epileptic seizures. However, research has revealed that without medical supervision, it can present problems under certain circumstances with anti-seizure medication. As for chemotherapy drugs, they are most often formulated to understand that the drug will undergo metabolism at a specific rate before entering the body. When CBD is introduced to the drug plan, the metabolism process is hampered or inhibited, resulting in higher concentrations of the drug to enter the bloodstream than intended.

Methods For Marketing Drugs

marketing consultantUnlike the past, today has a more educated audience around the topic of drugs. No matter the specific drug you’re discussing, there is a broader audience to understand the subject. Considering there’s more information than ever before, it makes it a more natural field to market than it previously once was. Since marketing has such a massive field attached to it, every field involved in it differs from one another. No matter the specifics of each, it’s an interesting subject to compare and contrast to one another. With the subject of marketing drugs, this has another barrier attached to it since there’s a stigma related to drugs.

For example, if you’re discussing marketing shoes, this is a lot simpler than marketing drugs. Since practically every person in the world wears shoes and understands their purpose, it’s a lot easier to market the matter than a field with a specific stigma surrounding it. Nonetheless, there is a massive field for marketing drugs. No matter the specifics of the drug, whether it’s the cannabis industry, pharmaceutical drugs, or even over-the-counter medication, they all have a designated marketing plan behind them. Down below, we’re going to discuss everything you’ll need to know about the methods for marketing drugs. Whether it’s the education, benefits, stigma, audience, and other information related to the matter, we’ll have it covered. Plus, we’ll discuss other side information in the field, such as Medicare costs and a marketing consultant. Let’s take a look!

Educate Audiences
First and foremost, with anything in the subject of drugs, it’s essential to educate audiences. Although the knowledge related to the broad field of drugs is more extensive than ever before, education is still crucial for growing the field. No matter the target audience of a specific drug and what it hopes to accomplish, educating them will expand the specifics of the drug more than ever. Whether the education paints a drug in a good or bad light, both are important for marketing. Plus, there is additional information such as Medicare costs that are great to discuss in the field. What people involved in the marketing of drugs need to understand is the complexities related in the manner. Since many people aren’t too knowledgeable about the specifics of an area and might have a pre-determined notion on it, it’s essential to discuss the facts. Nonetheless, educating through marketing can be as simple as sharing studies, creating videos and posts with facts, and various other information on the manner. Plus, since the world of drugs is such a large one, it’s vital to pinpoint the specifics of each.

 medicare costsExplain the Benefits
Right next to educating, the fundamental role of any form of marketing is to explain the benefits. Like anything else, people want to know how something is useful for them. Considering the world related to drugs is such a massive one, it’s a problematic notion altogether to pinpoint how the specifics of one is beneficial to every individual.

Nonetheless, this is a vital role in marketing for the right reason. If you think about it, no one buys anything unless they look at how it’ll help them. Even if they buy a gift for someone else, that gift is thought of as a way to help others. If you think about clothes or other various commodities people frequently buy, they buy them for the sole purpose they think they’ll look good in them. Of course, the practicality of clothes is essential, but people generally buy them to help their image in a sense. No matter the field you look into, they all share the same common goal of presenting the benefits and why they’ll be good for each individual to use. Even the most caring of people look at specific areas and what will benefit them. Since drugs are such a specific field for every person to consider, the field has an interest for everyone. Thus, why so many in the field turn to a marketing consultant to help list all of the benefits tied to the manner.

Change the Stigma
Similar to explaining the benefits, there is a stigma attached to drugs that should be removed. Of course, some fields are more severe than others and have a rightful perception. However, a lot of the time, that stigma is wrong. For example, the cannabis industry has seen a massive shift in the stigma surrounding the matter since the early days of its history. Previously, people thought marijuana to be purely evil and not meant for anyone to consume. Propaganda erupted and made up numerous fake studies on the matter and is the main reason why it’s not entirely legal throughout the U.S. yet.

However, with the stigma changing around the cannabis industry, more states have fully legalized it. As this shift in this direction moves forward, we’ll eventually see full legalization throughout the country at one point or another. Outside of just the cannabis industry, there is a massive stigma related to many fields in the drug world. Thus, it’s crucial for a marketing consultant and people involved in the drug world to understand what to do in the matter.

medicare costsKnow Your Audience (Reach Them)
Outside of everything related to the field, knowing your audience is arguably the most crucial role of drug marketing. Considering that not every person wants to hear the market plan related to a specific drug niche, it’s vital to pinpoint your audience. Of course, having a broad audience is undoubtedly a bright point for any company to accomplish; this isn’t the case with each company’s specifics. Think of it like this; not every person in the world will need to use an anxiety-relief drug; thus, why a company that creates an anxiety-relief drug will have to look into the specific audience that’ll have that need.

Recognize Flaws and Adjust
Outside of knowing your audience, it’s as crucial of a manner for recognizing flaws. Since not every marketing plan is filled with pure excellence, mistakes do happen. If you cannot recognize the flaws of your specific market, turn to a marketing consultant. Having a professional take hand at your specific goals will help you fully transform the entire process of drug marketing. Although this might appear to be a difficult task, it can happen quicker than most realize.

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